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What is the mechanism of renal autoregulation?

What is the mechanism of renal autoregulation?

Renal autoregulation is achieved primarily by a unique orchestrated action of two major mechanisms: the myogenic response and the macula densa tubuloglomerular feedback (MD-TGF) response.

What are two mechanisms by which autoregulation of renal blood flow occurs?

It is thought today, that RBF autoregulation is based on two mechanisms, the myogenic response (MR) and the tubuloglomerular feedback (TGF).

What is the purpose of the tubuloglomerular feedback mechanism?

Tubuloglomerular feedback is an intrarenal control mechanism designed to regulate the amount of salt entering the distal nephron.

What are the two mechanisms involved in autoregulation of GFR?

Autoregulation is necessary to prevent changes in GFR and RBF when blood pressure varies abruptly. Two systems are responsible for renal autoregulation: (1) a myogenic mechanism and (2) a tubuloglomerular feedback mechanism.

What are the three mechanisms that regulate renal flow?

Autoregulation of renal blood flow comprises three mechanisms: the myogenic response (MR), the tubuloglomerular feedback (TGF), and a third mechanism (3M).

What are the three aspects of autoregulation?

Myogenic, shear-dependent, and metabolic responses in autoregulation.

What are the two types of autoregulation of blood flow?

At least two different mechanisms contribute to renal autoregulation: the fast, myogenic, and the slower, tubuloglomerular feedback (TGF), responses.

What is the Tubuloglomerular mechanism?

Tubuloglomerular feedback is an adaptive mechanism that links the rate of glomerular filtration to the concentration of salt in the tubule fluid at the macula densa. A high [NaCl] and reabsorption rate at this site causes contraction of the afferent arteriole and a reduction in GFR.

What is tubuloglomerular feedback quizlet?

Tubuloglomerular feedback involves a feedback loop in which NaCl concentration of tubular fluid is sensed by the macula densa of the JGA and converted into a signal or signals that affect afferent arteriolar resistance and thus the GFR. A decrease in GFR (decrease in NaCl) causes vasodilation.

What is autoregulation of GFR?

The ability of the kidney to maintain constancy of the glomerular filtration rate (GFR) over a wide range of renal perfusion pressures is termed autoregulation.

What are the three mechanisms of autoregulation?

What are the 3 aspects of autoregulation?