Table of Contents
- 1 Which drugs increase myocardial oxygen supply?
- 2 What increases the demand for myocardial oxygen?
- 3 Which medications decreases myocardial oxygen demand and helps to relieve chest pain?
- 4 Which drug worsens angina?
- 5 Is imbalance between demand and supply of oxygen to the heart?
- 6 What are three medical procedures that help people with heart disease?
- 7 What is the drug of choice for acute attacks of angina?
- 8 Does morphine relieve chest pain?
Which drugs increase myocardial oxygen supply?
Phosphodiesterase inhibitors (amrinone, enoximone) have both an inotropic and a vasodilating effect. They decrease cardiac afterload, and increase blood supply to the myocardium; this compensates for the increase in myocardial oxygen consumption due to the increase in myocardial contractility.
What increases the demand for myocardial oxygen?
Heart rate, contractility, and ventricular-wall tension are the three factors that determine myocardial oxygen demand. An increase in any of these variables requires the body to adapt to sustain adequate oxygen supply to the heart.
Does aspirin increase myocardial oxygen demand?
In addition, aspirin is not likely to affect myocardial oxygen mismatches resulting from exertion or arterial spasm, but if these other causes of ischemia are treated, it may be possible to unmask the effect of aspirin.
Which medications decreases myocardial oxygen demand and helps to relieve chest pain?
Metoprolol (Lopressor, Toprol XL) These agents decrease myocardial oxygen demand by reducing heart rate, contractility, and arterial pressure. Shown to improve survival in patients with MI.
Which drug worsens angina?
Worsening of angina – Beta blockers can promote arterial spasm, meaning they cause the walls of the arteries to spasm and narrow, so they may actually worsen angina in people with variant angina (angina caused by spasm).
What is a common side effect of antianginal drugs?
Common side effects and precautions
| Drug class | Common side effects |
|---|---|
| 3. Calcium channel blockers | Constipation Headache Tachycardia Dizziness Rash Fatigue Flushing Nausea Oedema (notably of ankles) |
| 4. Long-acting nitrates | Postural hypotension Tachycardia (paradoxical bradycardia also reported) Throbbing headache Dizziness |
Is imbalance between demand and supply of oxygen to the heart?
Under certain pathologic states such as coronary artery disease, the supply of oxygen may be exhausted and an imbalance between supply and demand occurs which is translated into ischemia.
What are three medical procedures that help people with heart disease?
Common medical procedures for heart conditions
- Coronary angioplasty and stent implantation. Coronary angioplasty is a procedure that helps to improve blood flow to your heart.
- Thrombolytic therapy.
- Coronary artery bypass graft surgery (CABG)
- Artificial pacemaker surgery.
- Defibrillation.
- Heart valve surgery.
Does aspirin help myocardial ischemia?
Conclusion— These data suggest that an initial dose of 162 mg aspirin may be as effective as and perhaps safer than 325 mg for the acute treatment of ST-elevation myocardial infarction. Aspirin therapy is a cornerstone in the immediate treatment of ST-elevation myocardial infarction (STEMI).
What is the drug of choice for acute attacks of angina?
Sublingual nitroglycerin — Sublingual (under the tongue) nitroglycerin (NTG) is usually recommended to treat sudden attacks of angina and to prevent angina while engaging in activities that typically trigger angina, such as mowing the lawn, playing sports, or walking up a hill (especially in the cold).
Does morphine relieve chest pain?
Morphine was first used to relieve the chest pain associated with heart attacks in 1912 and has been used regularly ever since. Nitroglycerin has been used for more than 130 years for the relief of chest pain, also known as unstable angina. It works by relaxing blood vessels and allowing blood flow to increase.