What is HPMC polymer?

What is HPMC polymer?

HPMC is a water soluble nonionic cellulosic polymer in which some of the hydroxyl groups are substituted with methoxy and hydroxypropyl groups (Zarmpi et al., 2017). As a binder, HPMC is used at the concentration of 2%–5% w/w, however, it has been commonly used as tablet film coating polymer.

What is Methocel E4M premium?

METHOCEL™ E4M Premium is a premium quality, water-soluble cellulose ether polymer. It is based on non-ionic Hydroxypropyl Methylcellulose (HPMC) and provides viscosity of 4,000 cP at low addition levels.

What is Methocel used for?

METHOCEL™ 228 is a modified HPMC that is used as a thickener in tape joint compounds, crack fillers, and other flexible construction materials. METHOCEL™ 240 is a high molecular weight hydroxypropyl methylcellulose polymer that is used as a thickener in water based coatings, inks & adhesives.

What is Methocel K4M?

METHOCEL™ K4M is an HPMC thickener with moderate hydroxypropyl substitution. It is used as a thickener for coatings and adhesives and as a binder to improve green strength in ceramics. METHOCEL™ K4M is often used as a thickener in latex paints to control the viscosity and rheology of the formulation.

Is HPMC a synthetic polymer?

In formulation F12 and F13, synthetic polymers HPMC K100 and eudragit RL 100 were used in combination with semi-synthetic polymer CMEC individually. The drug release was found to be 98.7% and 93.4% at the end of 24 and 16 h.

Is hydroxypropyl cellulose toxic?

It is now an EU and FDA-approved food additive and is considered non-toxic to humans.

Is Methocel safe?

In addition, methylcellulose (METHOCEL™ A products) is Generally Recognized As Safe (GRAS) by the U.S. Food and Drug Administration. To support new drug applications in the United States, drug master files (DMFs) for these products are on file at the Bureau of Drugs of the U.S. Food and Drug Administration.

What is Benecel?

Benecel™ E10M is a high-purity, water-soluble, non-ionic, cellulose ether. It functions as a thickener, lather enhancer, lather stabilizer, water-binder, film-former, and co-suspending and co-emulsifying agent.

What is the use of carboxymethylcellulose sodium eye drops?

Carboxymethylcellulose is used in the treatment of dry eyes. It is used as a lubricant to relive irritation and discomfort due to dryness of the eyes or due to exposure of the eyes to wind or sun. Carboxymethylcellulose is a lubricant.

How to calculate the pH of HPMC K100?

Standard solution: Into a 50 ml Nessler cylinder pipette 1 ml of lead standard solution (20 ppm Pb) and dilute with water to 25 ml. Adjust with dilute acetic acid or dilute ammonia solution to a pH between 3.0 and 4.0, dilute with water to about 35 ml and mix.

How is hydroxypropyl methylcellulose K100 chemical analysis?

Procedure for chemical analysis for the Hydroxypropyl Methylcellulose k100 in pharmaceutical quality control. 1. Description White or yellowish white, fibrous or granular powder, almost odorless, hygroscopic after drying. 2. Solubility Practically insoluble in hot water, in acetone, in ethanol, in ether, toluene and in chloroform.

What kind of emulsifier is hydroxypropyl methylcellulose ( HPMC )?

Hydroxypropyl methylcellulose ( HPMC ) is a substituted propylene oxide with methylcellulose. H 1815 (OTTO) HPMC, K100 Cas 9004-65-3 – used as an emulsifier, thickening and suspending agent similar to animal gelatin.

What does hypromellose stand for in medical category?

Infobox references. Hypromellose (INN), short for hydroxypropyl methylcellulose (HPMC), is a semisynthetic, inert, viscoelastic polymer used as eye drops, as well as an excipient and controlled-delivery component in oral medicaments, found in a variety of commercial products.