What is considered high alkaline phosphatase?

What is considered high alkaline phosphatase?

The normal range of alkaline phosphatase in the blood is 20 to 140U/L, although this can vary from lab to lab. Children and pregnant women can have significantly higher levels of the enzyme in their blood [1]. Values above 130 U/L are usually considered to be high.

What is a normal alkaline phosphatase level by age?

For men and women older than age 18, an ALP level between 44 and 147 U/L is considered normal. The normal range for children is higher than that for adults, especially for infants and teens because their bones are growing rapidly.

What does low alkaline phosphatase indicate?

Low levels of alkaline phosphatase may indicate hypophosphatasia, a rare genetic disease that affects bones and teeth. Low levels may also be due to a deficiency of zinc or malnutrition. To learn what your results mean, talk to your health care provider.

What is the treatment for high alkaline phosphatase?

A reduction in serum ALP was also seen in the euparathyroid subjects (2.4 +/- 0.77 to 2.2 +/- 0.64 mu kat/l, p = 0.03). This study indicates that treatment with active vitamin D is effective in reducing the increased bone turnover seen in subjects with both primary and secondary HPT.

What causes high alkaline phosphatase levels?

The most common causes of high ALP levels include: liver conditions, often bile duct obstructions. gallbladder conditions, usually gallstones. bone conditions, such as abnormal growths and occasionally cancers.

Can fatty liver cause high alkaline phosphatase?

Fatty liver linked to obesity often causes a rise in liver transaminases but not a solitary rise in alkaline phosphatase. Bone pathology causes of elevated alkaline phosphatase include Paget’s disease, hyperparathyroidism, osteomalacia, metastatic bone disease and a recent fracture.

Is a low alkaline phosphatase bad?

Low levels Having lower-than-normal ALP levels in your blood is rare, but it can indicate malnutrition, which could be caused by celiac disease or a deficiency in certain vitamins and minerals.

Can low vitamin D cause low alkaline phosphatase?

Thus, vitamin D deficiency is usually accompanied by normal blood levels for calcium and phosphorus, high-normal or elevated levels of PTH, normal to elevated levels of total alkaline phosphatase, a low 24-hour urine calcium excretion rate, and low levels of total 25(OH)D.

Can low vitamin D cause high alkaline phosphatase?

Elevated serum alkaline phosphatase (ALP) level is an essential marker for the diagnosis of vitamin D deficiency (1). Some cases of vitamin D deficiency are diagnosed accidentally on the basis of elevated ALP levels.

What is normal level of alkaline phosphatase?

Normal Values. The normal value for alkaline phosphatase is 53 to 128 U/L for a 20- to 50-year-old man and 42 to 98 U/L for a 20- to 50-year-old woman. Pregnant women typically have higher alkaline phosphatase values due to contributions from the placenta.

What does high Alk Phos mean?

A high alk phos level does not reflect liver damage or inflammation. A high alk phos level occurs when there is a blockage of flow in the biliary tract or a buildup of pressure in the liver–often caused by a gallstone or scarring in the bile ducts.

What medications can make alkaline phosphatase high?

Many common over-the-counter and prescription drugs can elevate alkaline phosphatase levels. For example, hypertension drugs such as propanolol or verapamil or gout treatments such as allopurinol can raise levels.

Values above 130 U/L are usually considered to be high. Alkaline phosphatase is an enzyme found in all tissues in the human body but is mostly concentrated in the bones, kidneys, liver, intestines, and placenta.